What is the first action to take in response to digoxin toxicity?

The first action to take in response to digoxin toxicity is to stop administration of digoxin and potassium-wasting diuretics. This is essential because digoxin has a narrow therapeutic index, meaning the difference between therapeutic and toxic doses is small. When toxicity is suspected, continuing the drug could exacerbate the patient's condition and lead to severe consequences, such as arrhythmias or other cardiac complications.

Stopping potassium-wasting diuretics is also critical because these medications can lead to hypokalemia (low potassium levels), which can further increase the risk of digoxin toxicity. Low potassium levels can enhance the cardiac effects of digoxin, including the risk of life-threatening arrhythmias.

By prioritizing the cessation of these medications, the healthcare provider is addressing the root causes of toxicity and mitigating the potential for further harm. Immediate intervention focuses on stabilizing the patient by removing the offending agents responsible for the toxic reaction, allowing for subsequent treatment options to be considered.